Nil Ratan Sircar Medical College & Hospital (NRSMC&H)

WELCOME TO HAEMATOLOGY DEPARTMENT


History and About Hematology Department, NRS Medical College and Hospital                                                                                              
           The Hematology journey was started long back in around 1972. The hematology wing, at N.R.S. Medical College started as a unit under the department of medicine to provide the needs of hematology patients. It commenced with a single room with a very small space for a laboratory. The unit consisted of a faculty (teacher) trained in hematology, who was posted under the department of medicine, along with one technician & a group D staff. The unit in this initial phase was headed by Dr Sandhya Ghose (1972-1974), Dr Manju Dutta Chaudhuri (1974 - 1980) and Dr Madan Mohan Rakshit (1980 -1990) sequentially. A total of ten beds and two-house physicians were allotted from the department of medicine to the unit. The activities included-outpatient clinic-twice in a week, indoor admission and attending referred cases. Basic instruments were scanty - 1-2 monocular microscopes, a water bath, a few Wintrobe and Westergren tubes, a couple of centrifuge machines, and a few bone-marrow aspiration needles. The faculty in-charge of the unit had to work overtime single handedly to provide adequate hematology services as well as teaching students. After about a decade, the unit was provided additional space, better ward facilities and some additional essential items. In spite of repeated efforts nothing substantial was achieved. Beginning of a new era Dr. Malay Kumar Ghosh (June 1990 – February 2013) joined the department in mid-nineties, he was fortunate enough to visit few established hematology setups in the country. He got inspired & realized that to sustain this specialty, it needs to transform the existing set up into a comprehensive hematology department, outside the prevailing domain of medicine. Dr Ghosh was a post-graduate in medicine with exclusive hematology training under Prof. Sandhya Ghosh besides training in general medicine. He was also fortunate enough to be posted as a clinical tutor in the prestigious hematology department of Calcutta School of Tropical Medicine (first time in the history of hematology in West-Bengal). Bolstering of the department by younger generation Dr. Maitreyee Bhattacharya, was headed the department from February 2013 to August 2014, joined as a clinical tutor in late nineties when only a post of clinical tutor was sanctioned by the health department. With her intense involvement, both Dr. Ghosh and Dr. Bhattacharyya embarked upon an intense drive for up progression of the hematology service and academic activities. In the beginning of 2000, it was officially declared an independent department of its own-one dream fulfilled. During this time the hematology department gradually started its journey for induction into the national field. With the initiative of Prof. Ghosh N.R.S. Medical College became the principal center for ICMR sponsored multicenter - JAY VIGYAN MISSION PROJECT for assessing the most recent status of thalassemia burden in the country. During this period, the relentless persuasion for the upgradation continued ceaselessly. New posts were created for professor, associate professor, assistant professor & clinical tutors along with nonacademic Senior Residents. DM course in Clinical Hematology was permitted to start from 2009 and got recognized in 2012 at the time of the final examination of the first batch.
Department had three seats for DM (Clinical Hematology) from 2013. Subsequently the department was headed by Dr Prantar Chakrabarty (August 2014 –June 2019) followed by Dr Tuphan Kanti Dolai from June 2019 to till now. Since 2019 there has been a major development in all aspects of Hematology. Presently the department runs four seats for DM (Clinical Hematology) from 2023.
In February 2009, first Bone Marrow Transplantation was done in the Department of Hematology, NRS Medical College and Hospital. This center did the first autologous as well as allogeneic stem cell transplantation in the Eastern part of India. This is the first center in India that did stem cell transplantation under the state Government Hospital in India. Initially the BMT unit was started with a single room with only air conditioning facilities. Subsequently transformed to three bedded non-HEPA filter facilities in 2015. Four bedded state of the art modular Bone Marrow Transplantation units started functioning in December 2021. The BMT unit of NRSMCH, still now (June 2024) did 122 stem cell transplants successfully. Now the center is well equipped with state of art stem cell transplant facilities and able to perform all types' stem cell transplantation procedures (Autologous, Allogeneic with MSD, MUD, Haploidentical and UCBT) and CAR T cell therapy. To serve the people of West Bengal and adjacent parts of countries, NRS Hematology is the largest Hematology center in the Eastern part of India. Today in June 2024, the Hematology department had 66 (sixteen) indoor beds and 15 (fifteen) Outdoor beds.  Pre-Natal-Diagnosis (PND) for thalassemia and sickle cell anemia started in July 2013. As of now (June 2024), the total number of cases was 1578 and 523 affected fetuses were identified. To strengthen the laboratory services, the department got a sanctioned dedicated post of Professor, associate professor, assistant professor and senior resident of Hematopathology. Presently the department has Molecular Laboratory, Coagulation Laboratory, Hemostasis Laboratory, Hemolytic Laboratory and other advanced techniques.  Today the hematology department of N.R.S Medical College has made a position in the hematology map of India as well as In the World.

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Publications


Publications (0ct 2022 to Sept 2023)

1. Pradhan, Sayantan; Hore, Samrat; Maj, Suman Kumar,.. Dolai, Tuphan Kanti "Study of Epidemiological Behaviour of Malaria and Its Control in the Purulia District of West Bengal, India (2016-2020)". Vol-12. 630, Scientific Reports, 2022.

2. Delimpasi, Sosana; Mateos, Maria Victoria; Aune,... Dolai, Tuphan Kanti; "Efficacy and Tolerability of Once-Weekly Selinexor, Bortezomib and Dexamethasone in Comparison with Standard Twice-Weekly Bortezomib and Dexamethasone in Previously Treated Multiple Myeloma with Rernal Impairment: Subgroup Analysis from the BOSTON Study" Molecular Biology Reports 2022.

3. Dolai, Tuphan Kanti; De, Rajib; Sen, Ankita; Baul, Shuvra Neel; Mitra, Sumit; Bhattacharya Subham: Mondal Indrani; Mukhopadhyay, Kaushik; Chattopadhyay, Arnab; Dutta, Shyamali; "Pattern of Autologous Stem Cell Transplants at a Tertiary Care Government Hospital, with Emphasis on Transplant Outcomes with Pre-Harvest CD34 + Level". Vol-5, 60, Blood Cell Therapy 2022.

4. Dutta, Atreyee; De, Rajib; Dolai, Tuphan Kanti; Halder, Ajanta; "Analyzing the Relation Between Cytokine IL-2 And Cytogenetic Abnormalities In Acquired Aplastic Anemia Patients" Contermporary Medical Biotechnology Research For Human Health (57-65) 2022.

5. Sen Ankita; Sen Adit; Dolai Tuphan Kanti; "Diagnostic Dilemma of Hemoglobinopathies Using High Performance Liquid Chromatography Alone: A Case Report from A Resource-Constrained Setting". Hemoglobin Vol-46, (256-259) 2022.

6. Rahaman, Motiur; Mukherjee, Mandrita; Bhattacharya,.. Dolai, Tuphan Kanti; Chakravorty, Nishant: "Exploring the Crosstalk Between Long Non-Coding RNAs and Micrornas to Unravel Potential Prognostic and Therapeutic Biomarkers in (-Thalassemia". Molecular Biology Reports Vol.-49, (7057-7068) 2022.

7. Sen, Ankita; Sahana, Pranab Kumar; Chakrabarti, Prantar; Ghosh, Pramit; Dolai, Tuphan Kanti; De, Rajib; "Abnormal Glucose Homeostasis in Patients of Hbe[-Thalassemia: Prevalence and Possible Pathogenesis Using the Oxford HOMA Model" Journal of Hematology and Allied Sciences, Vol. 2, (46-54)2022.

8. Dolai, Tuphan Kanti; Jain, Manisha; Mahapatra, Manoranjan; "ldiopathic Aplastic Anemia: Indian Perspective" Indian Journal of Hematology and Blood Transfusion, Vol.-39, (357-370) 2023.

9. Baul, Shuvra Neel; Baveja, Avriti;, Mandal, Prakas Kumar; De, Rajib; Dutta, Shyamali; Dolai, Tuphan Kanti; "A Glimpse into Translocation (8;21) In Acute Myeloid Leukemia: Profile and Therapeutic Outcomes from A Tertiary Care Hematology Center from East India "Journal of Hematology and Allied Sciences Vol.-2,(85-90) 2022.

10.De Rajib; Jena Rabindra Kumar; Vidhatri Rishu; Dolai Tuphan Kanti; Baul Shuvra Neel; "Differential Erythrocyte Phosphatidylserine Exposure Is Associated with Variations in Clinical and Hemostatic Parameters: A Study Involving E-] and Thalassemia Compared to Normal Population" Blood Vol.-140, Supplement 1, (5367-5368) 2022 American Society of Hematology.

11.Dolai Tuphan Kanti, Hematology Education and Training in India in 2022-Scope and The Hope 2022. 12. Pradhan Sayantan; Dolai Tuphan Kanti; Mandal Amit Kumar; "Malaria Epidemiology and ts Control During The COVID-19 Pandermic Situation in India"Curr. Sci \Vol.123, (1299), 2022.

13. Kazi, Bilal Shoeb; Dolai, Tuphan Kanti; Sen, Ankita; Das, Reena; "Pyruvate Kinase Deficiency: A Rare Cause of Hemolytic Anemia: A Case Report From North-Eastern India". Journal Of Hematology and Allied Science, Vol- 2, (99-100) 2022.

14. Menon, Hari; Singh, Pawan Kumar; Bagal, Bhausaheb; Dolai, Tuphan; Jain, Ankita; Chaudhri, Antara: "Minimal Residual Disease in The Management Of B-Cell Acute Lymphoblastic Leukemia: A Systematic Review of Studies from Indian Settings" Indian Journal Of Hematology And Blood Transfusion 11-Jan 2023.

15. Mathews, Vikram; Korula, Anu; Chakrapani, Anupam... Dolai Tuphan Kanti "Management Of B-Cell Lineage Acute Lymphoblastic Leukemia: Expert Opinion from An Indian Panel Via Delphi Consensus Method" Frontiers in Oncology, Vol.-13, 2023.

16.Patel Ankt; Bhatt Niraj; Prakash, SS; Biswas, Ghanashyam; Nagarkar, Rajnish; Roy, Bodhisatta; Samal, Priyanka; Agrawal, Narendra; Meshram, Sushil; Kaushal, Ashish; "Rituximab Biosimilar for the Treatment of Diffuse Large B-Cell Lymphoma: A Phase 3 Randomized Study in India" Cancer Chernotherapy and Pharmacology, Vol.91, (457-468) 2023.

17. Basu, Subhangi; Rahaman, Motiur; Dolai, Tuphan Kanti; Shukla, Praphulla Chandra; Chakravorty, Nishant; "Understanding the Intricacies of Iron Overload Associated With 1-Thalassemia: A Comprehensive Review 2023".

18.Pradhan Sayantan; Hore, Samrat; Roy, Stabak; Manna, Simi; Dam, Paulami; Mondal, Rittick; Ghati, Amit; Biswas, Trishanjan; Sharma, Supriya; Singh, Waikhom Somraj; "Geo-Environmental Factors and the Efectiveness of Mulberry Leaf Extract in Managing Malaria: A Study in Purulia District, West Bengal, India 2023".

19. Panja Amrita; Das, Brahmarshi; Dolai, Tuphan Kanti; Choudhury, Sujata Maíti; "The Key Genetic Determinants Behind the Phenotypic Heterogeneity of HBE/J-Thalassemia Patients and The Probable Management Strategy 2023".

20.Ghosh Kaustav; Baul Shuvra Neel; Dolai Tuphan Kanti; "Hodgkin Lymphoma Patient Presenting as Superior Vena Cava Syndrome in A Patient Suffering from Myotonia Congenita: A Rare Case Scenario" Journal of Hematology And Allied Sciences, Vol.-3, (34-36) 2023.

21.Pradhan, Sayantan; Hore, Samrat; Roy, Stabak; Manna, Simi; Dam, Paulami; Mondal, Rittick; Ghati, Amit Biswas, Trishanjan; Shaw, Subhajit; Sharma, Supriya; "Ge0-Environmental Factors and The Effectiveness of Mulberry Leaf Extract in Managing Malaria"Scientific Reports, Vol.-13, 2023.

22.Sarkar S, Thapa R, Naushin F Gupta S, Bhar B, De R, Bhattacharya J. "Antibiotic-Loaded Smart Platelet: A Highly Effective Invisible Mode of Killing Both Antibiotic-Sensitive and -Resistant Bacteria" ACS Omega. 2022 Jul 1:7(28):24102-24110.

23.Rajib De., et al. "Adenovirus an Increasing Concern in West Bengal - Manifestation, Detection, Prevention and Treatment". Acta Scientific2023.

24. Seth T, Garg K, Mandal PK, Datta A, Verma S, Hanagavadi S, Thota UR. Cost-effectiveness analysis of low-dose prophylaxís versus on-demand treatment for moderate-to-severe hemophilia A in India. Hematology. 2023 Dec31;28(1);2277497.

25.Mandal PK, Garg M, Chakrabarti P Bhowmik A, Gantait D, Dolai TK. Bone health assessment in haemophilic arthropathy: A single centre study from Kolkata, West Bengal, India. The Journal of Haemophilia Practice.;8(1):183-8.

26. Baul Shuvra Neel. Mondol Kusumita, Saha Sandeep, Bhakat Biva, Sharma Abhishek, De Rajib, Dolai Tuphan Kanti "Etiological Heterogeneity of Pancytopenia VWithout Organomegaly and Lymphadenopathy From A Tertiary Care Hematology Centre Of Eastern India:" 6.5 (2023).

27.Sharma P Naseem S, Varma N, Et Al. Monocyte Distribution Width (MDW) In Patients With COVID-19: An Indicator of Disease Severity [Published Online 2023 May 20]. Indian J Hematol Blood Transtus. 2023

28. Resident Corner: Roy Shipla "Dyskeratosis Congenita in A 6-Year-0ld Boy"J Hematol Allied Sci, 2023.

29.Ghosh K "A Rare Cause of Seizure with Benign Course in A Child" JHematol Alied Sci, 2023.

30.Roy S, Ghosh K, Mandal PK "Hematuria in A Young Severe Hemophilia Patient- A Case Report on A Rare Radiological Finding" J Hematol Allied Sci, 2023.

31.Roy,S "Rare cause of pancytopenia in a 5-year-old boy" J Hematol Allied Sci 2023; 3:44-5.

32. Ghosh K, Baul SN, Dolai TK "Hodgkin Lymphoma Patient Presenting as Superior Vena Cava Syndrome in A Patient Suffering from Myotonia Congenita: A Rare Case Scenario" JHematol Allied Sci 2023; 3:34-6

33. Ghosh, Kaustav; Sanyal, Chirasree; Mandal, Prakas Kumar. Anaplastic Lymphoma Kinase Positive Larae B-Cell Lymphoma Mimicking as Plasma Cell Neoplasm: A Rare Case Report. Journal of Applied Hematology 14(3) : P 252-254, Jul-Sep 2023.

34. Seth T, Garg K, Mandal PK, Datta A, Verma S, Hanagavadi S, Thota UR. Cost-effectiveness analysis of low-dose prophylaxis versus on-demand treatment for moderate-to-severe hemophilia A in India. Hematology. 2023 Dec 31;28(1):2277497.

35. Sanyal C: Cause Of Pancytopenia in A Young Female: Think Differently Journal of Hematology and Allied

 

Academic Details


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Faculty Details

Image Name Registration No. Designation Email ID Phone Publications Services
Dr Tuphan Kanti Dolai (MBBS, MD(Medicine) DNB(Medicine) DM) Professor & Head View View
Dr Rajib De (MBBS,MD,DM) Professor View View
Dr Prakash Kr Mandal (Detailed from STM) (DM ) Professor View View
Dr. Sandeep Saha (MBBS, MD, DM (Heamatology)) Associate Professor View View
Dr. Shuvra Neel Baul (MBBS, MD(Medicine) DNB(Medicine) DM(Haematology)) Associate Professor View View
Dr Subham Bhattacharya (MBBS, MD(Pediatri c Medicine) DM) Assistant Professor View View
Dr Abhishek Sharma Assistant Professor --
Dr. Shipla Roy (MBBS, MD (Pathology), DNB (Pathology), DM (Clinical Hematology) RMO cum Cl. Tutor --

Residents Details

Image Name Registration No. Position Publications Services
Dr Abhishek Kumar, Dr Apurba Banerjee Post Graduate Trainees (3rd Year) --
Dr Kaustav Ghosh, Dr Chirasree Sanyal Post Graduate Trainees (2nd Year) --
Dr Praveen Kumar Jha, Dr Praveen Kumar Post Graduate Trainees (1st Year) --

Non Teaching Staff

Image Name Department Position
Dr Aditi Sen Haematology Molecular Biologist
Dr Sarmistha De, Dr Tuhin Shubhra Gain, Dr Riya Mukherjee Haematology Medical Officer